Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078709 | 0.93 | L3MBTL1 (0.37) | L3MBTL1NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL10198713 | 0.91 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL14143640 | 0.87 | L3MBTL1 (0.49) | L3MBTL1NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL19445566 | 0.80 | L3MBTL1 (0.37) | L3MBTL1NPC1RAB9ACYP1A2TSHR | |
| SCHEMBL5862900 | 0.72 | L3MBTL1 (0.73) | L3MBTL1NPC1RAB9ACYP1A2TERT | |
| SCHEMBL18759318 | 0.70 | CFD (0.61) | TERTCFDSPHK2HDAC1KDM4E | |
| SCHEMBL10078124 | 0.70 | TAAR1 (0.45) | MAOB | |
| SCHEMBL22702202 | 0.69 | MAOB (0.47) | NPC1RAB9ACYP1A2TSHRNFKB1 | |
| SCHEMBL880647 | 0.68 | PTGES (0.32) | NPC1RAB9A | |
| SCHEMBL404359 | 0.68 | CYP1A2 (0.58) | NPC1RAB9ACYP1A2TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468711-A2 | Facially amphiphilic polyaryl and polarylalkynyl polymers and oligomers and uses thereof | The Trustees Of The University Of Pennsylvania (US) | 2012-06-27 | — | — | EP | disclosed |
| EP-2433627-A1 | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer | The Trustees Of The University Of Pennsylvania (US) | 2012-03-28 | — | — | EP | disclosed |
| EP-2301349-A2 | Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer | The Trustees of The University of Pennsylvania (US) | 2011-03-30 | — | — | EP | disclosed |