Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 4/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075470 | 0.85 | IGF2R (0.36) | PDE4DPTPN1ALDH1A1LGALS3LGALS8 | |
| SCHEMBL20147800 | 0.84 | TK1 (0.38) | MAPK1PDE4DOGAPTPN1SLC5A2 | |
| SCHEMBL4320956 | 0.79 | MAPK1 (0.52) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL25625445 | 0.79 | MAPK1 (0.52) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL17339700 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL30232030 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL24531345 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL25484566 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL17297124 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 | |
| SCHEMBL18769744 | 0.78 | GAA (0.48) | MAPK1LGALS3LGALS8LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021514-A1 | HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY | PHASERX, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-20110281934-A1 | MICELLES OF HYDROPHILICALLY SHIELDED MEMBRANE-DESTABILIZING COPOLYMERS | PHASERX, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110142951-A1 | MICELLES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | UNIVERSITY OF WASHINGTON (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110143435-A1 | POLYMERIC CARRIER | UNIVERSITY OF WASHINGTON (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110123636-A1 | MICELLIC ASSEMBLIES | UNIVERSITY OF WASHINGTON (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281934-A1 | MICELLES OF HYDROPHILICALLY SHIELDED MEMBRANE-DESTABILIZING COPOLYMERS | LNPK, ANXA5, MTDH | MAPK1 3557/4885PDE4D 4563/4885OGA 3064/4885 |
| US-20110142951-A1 | MICELLES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ACTB, MTHFD1, SSBP1 | MAPK1 4238/4885PDE4D 3657/4885OGA 2521/4885 |
| US-20110123636-A1 | MICELLIC ASSEMBLIES | CLPX, VCL, ANXA5 | MAPK1 3469/4885PDE4D 4393/4885OGA 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.