SCHEMBL10078879

SCHEMBL10078879

COCCOC(=O)Nc1cccc(C(C)(C)C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.42
CSNK2A2 P19784 1/20 0.39
CSNK2A1 P68400 1/20 0.39
TSHR P16473 1/20 0.39
KIF18A Q8NI77 1/20 0.39
SYK P43405 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 2/20 0.36
TP53 P04637 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
EDNRB P24530 3/20 0.36
EDNRA P25101 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
GRM5 P41594 1/20 0.36
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10068157 0.88 HPGD (0.47) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL10078953 0.86 MGLL (0.50) TSHRNPC1RAB9AMEN1KMT2A
SCHEMBL10068152 0.84 RAB9A (0.45) CSNK2A2CSNK2A1TSHRNPC1RAB9A
SCHEMBL10078880 0.82 NPC1 (0.47) RXFP1TSHRKIF18ANPC1RAB9A
SCHEMBL10068162 0.80 PIK3CG (0.45) RXFP1CSNK2A1RAB9AMEN1POLB
SCHEMBL10084528 0.80 CHRNB2 (0.55) RXFP1CSNK2A2CSNK2A1TSHRSYK
SCHEMBL10220181 0.79 LCK (0.45) RXFP1KIF18ASYKNPC1RAB9A
SCHEMBL10068147 0.76 GAA (0.51) RXFP1TSHRSYKNPC1RAB9A
SCHEMBL29739290 0.75 ALDH1A1 (0.47) RAB9AMEN1KMT2ALMNATP53
SCHEMBL29177265 0.75 RAB9A (0.49) CSNK2A1KIF18ANPC1RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119645-B2 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2012-02-21 US disclosed
US-20090291969-A1 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291969-A1 Fungicide hydroximoyl-tetrazole derivatives HAAO, HAO1, CYP51A1 RXFP1 3865/4885CSNK2A2 2736/4885CSNK2A1 2576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.