Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069340 | 0.82 | NOTUM (0.33) | NOTUM | |
| SCHEMBL146460 | 0.78 | AR (0.31) | — | |
| SCHEMBL27371223 | 0.77 | CA2 (0.30) | CA2 | |
| SCHEMBL14483362 | 0.76 | GLA (0.38) | — | |
| SCHEMBL145873 | 0.74 | AR (0.32) | NOTUM | |
| SCHEMBL27618380 | 0.74 | — | — | |
| SCHEMBL101627 | 0.74 | KIF11 (0.32) | — | |
| SCHEMBL28126058 | 0.73 | KDM1A (0.33) | — | |
| SCHEMBL103466 | 0.73 | IDO1 (0.35) | NOTUM | |
| SCHEMBL2331156 | 0.73 | GLA (0.35) | CA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063359-B | Binary asymmetric organic lithium salt, electrolyte and lithium battery | 蓝固(湖州)新能源科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118063359-A | Binary asymmetric organic lithium salt, electrolyte and lithium battery | 蓝固(湖州)新能源科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-116891466-A | Pyrazole-containing dithiazole carboxamide derivative and preparation method and application thereof | 南开大学 | 2023-10-17 | — | — | CN | claimed |
| WO-2022026823-A1 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2022-02-03 | — | — | WO | claimed |
| CN-110818598-A | Cathepsin inhibitor and preparation method and application thereof | 沈阳药科大学 | 2020-02-21 | — | — | CN | claimed |
| CN-108676028-A | Dithiophosphinic acid compound and preparation method and application thereof | 中国人民解放军国防科技大学 | 2018-10-19 | — | — | CN | claimed |
| CN-108026089-A | Isoxazoline substituted benzamides and analogs as pesticides | 先正达参股股份有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-106831609-A | A kind of 6 sulfonate group pyrimidine salicylic acid compounds and its preparation method and application | 华中师范大学 | 2017-06-13 | — | — | CN | claimed |
| US-8796250-B2 | Diaryl ureas for diseases mediated by PDGFR | BAYER HEALTHCARE LLC (US) | 2014-08-05 | — | — | US | claimed |
| CN-102827056-B | N-aryl-substituted pyrrolidone derivative and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-07-23 | — | — | CN | claimed |
| US-20010016659-A1 | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC | 2001-08-23 | — | — | US | claimed |
| US-20010011136-A1 | omega-carboxyyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC | 2001-08-02 | — | — | US | claimed |
| US-20010011135-A1 | Omega-carboxyaryl subsituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC | 2001-08-02 | — | — | US | claimed |
| US-6159973-A | Aromatic amides, their preparation process, the compositions containing them and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2000-12-12 | — | — | US | claimed |
| WO-2000059509-A1 | PHTHALAZINE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | NOVARTIS AG (CH) | 2000-10-12 | — | — | WO | claimed |
| EP-0805795-B1 | NOVEL AROMATIC AMIDES, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO SA (FR) | 2000-08-23 | — | — | EP | claimed |
| WO-2000041698-A1 | φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | claimed |
| WO-2000042012-A1 | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | claimed |
| US-6013837-A | E.G.,4-(2-(3,4,5-TRICHLORO PHENYL) 1-FLUOROCYCLOPROPYL)-N-(2-METHYL PHENYL)BENZAMIDE; PARTICULAR USE AGAINST ARTHROPODS, HELMINTHS AND MOLLUSCS; INSECTICIDES; ACARICIDES; NEMATICIDES; PHOTOSTABILITY; NONTOXIC TO MAMMALS | HOECHST MARION ROUSSEL (FR) | 2000-01-11 | — | — | US | claimed |
| US-4094661-A | 3-IMINO PHTHALIDES | MONSANTO COMPANY (US) | 1978-06-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011135-A1 | Omega-carboxyaryl subsituted diphenyl ureas as raf kinase inhibitors | BRAF, RAF1, ARAF | NOTUM 788/4885CA1 4830/4885CA2 4539/4885 |
| US-20010011136-A1 | omega-carboxyyaryl substituted diphenyl ureas as raf kinase inhibitors | BRAF, ARAF, RAF1 | NOTUM 838/4885CA1 4687/4885CA2 3850/4885 |
| US-20010016659-A1 | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors | BRAF, RAF1, ARAF | NOTUM 940/4885CA1 4853/4885CA2 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.