Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597545 | 0.98 | THRB (0.49) | THRBTHRASLC29A1NAAADGKA | |
| SCHEMBL13327007 | 0.92 | THRB (0.45) | THRBTHRASLC29A1NAAAHTR2C | |
| SCHEMBL33174 | 0.92 | THRB (0.58) | THRBTHRANAAADGKAHTR2C | |
| SCHEMBL33242 | 0.91 | THRB (0.45) | THRBTHRASLC29A1NAAADGKA | |
| SCHEMBL672310 | 0.91 | THRB (0.44) | THRBTHRASLC29A1DGKAMAPT | |
| SCHEMBL28146 | 0.90 | THRB (0.56) | THRBTHRANAAADGKAHTR2C | |
| SCHEMBL31530004 | 0.89 | THRB (0.43) | THRBTHRASLC29A1NAAAHTR2C | |
| SCHEMBL13380195 | 0.87 | THRB (0.43) | THRBTHRASLC29A1 | |
| SCHEMBL13327014 | 0.86 | THRB (0.42) | THRBTHRASLC29A1DGKAMAPT | |
| SCHEMBL673561 | 0.86 | THRB (0.48) | THRBTHRASLC29A1DGKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588535-B1 | AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-2588514-B1 | GRAFTED COMPOUNDS FORMED FROM AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-03-18 | — | — | EP | disclosed |
| US-8796390-B2 | Grafted compounds formed from aziridinyl-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-05 | — | — | US | disclosed |
| US-8796390-B2 | Grafted compounds formed from aziridinyl-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-05 | — | — | US | disclosed |
| US-8779068-B2 | Aziridinyl-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-8779068-B2 | Aziridinyl-containing compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130102731-A1 | GRAFTED COMPOUNDS FORMED FROM AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102731-A1 | GRAFTED COMPOUNDS FORMED FROM AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130090434-A1 | AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090434-A1 | AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2012005814-A1 | GRAFTED COMPOUNDS FORMED FROM AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012005932-A2 | AZIRIDINYL-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-12 | — | — | WO | disclosed |