Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16597545 | 0.91 | THRB (0.49) | THRBTHRASLC29A1HTR2CMAPT | |
| SCHEMBL10079025 | 0.89 | THRB (0.51) | THRBTHRASLC29A1HTR2CMAPT | |
| SCHEMBL33174 | 0.84 | THRB (0.58) | THRBTHRAHTR2CMAPTRECQL | |
| SCHEMBL13327007 | 0.84 | THRB (0.45) | THRBTHRASLC29A1HTR2CMAPT | |
| SCHEMBL672310 | 0.84 | THRB (0.44) | THRBTHRASLC29A1MAPT | |
| SCHEMBL28146 | 0.83 | THRB (0.56) | THRBTHRAHTR2CMAPTALDH1A1 | |
| SCHEMBL33242 | 0.81 | THRB (0.45) | THRBTHRASLC29A1HTR2CMAPT | |
| SCHEMBL673561 | 0.79 | THRB (0.48) | THRBTHRASLC29A1MAPTALDH1A1 | |
| SCHEMBL13327014 | 0.79 | THRB (0.42) | THRBTHRASLC29A1MAPT | |
| SCHEMBL13327010 | 0.78 | THRB (0.41) | THRBTHRASLC29A1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096940-A1 | LIPID COMPOUNDS | SPARK THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |