Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33174 | 0.95 | THRB (0.58) | THRBTHRADGKAMAPTRECQL | |
| SCHEMBL16597545 | 0.91 | THRB (0.49) | THRBTHRAMAPK1ALDH1A1DGKA | |
| SCHEMBL673561 | 0.90 | THRB (0.48) | THRBTHRAMAPK1ALDH1A1DGKA | |
| SCHEMBL10079025 | 0.90 | THRB (0.51) | THRBTHRADGKAMAPTRECQL | |
| SCHEMBL672310 | 0.88 | THRB (0.44) | THRBTHRADGKAMAPT | |
| SCHEMBL13327007 | 0.85 | THRB (0.45) | THRBTHRAMAPK1ALDH1A1MAPT | |
| SCHEMBL13327014 | 0.83 | THRB (0.42) | THRBTHRADGKAMAPT | |
| SCHEMBL31530004 | 0.83 | THRB (0.43) | THRBTHRAMAPK1ALDH1A1MAPT | |
| SCHEMBL674504 | 0.82 | HRH3 (0.44) | THRBTHRAALDH1A1GAAL3MBTL1 | |
| SCHEMBL9327544 | 0.82 | TSHR (0.43) | THRBTHRAALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456746-B1 | TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE | BRIDGESTONE CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-11292771-B2 | Amidine catalyst for curable compositions | SIKA TECHNOLOGY AG (CH) | 2022-04-05 | — | — | US | disclosed |
| CN-107771175-B | Amidine catalysts for curable compositions | SIKA技术股份公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-3851489-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | BRIDGESTONE CORPORATION (JP) | 2021-07-21 | — | — | EP | disclosed |
| EP-3757094-A1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECHNOLOGY AG (CH) | 2020-12-30 | — | — | EP | disclosed |
| US-10875937-B2 | Terminal-modified conjugated diene polymer, rubber composition and rubber article | BRIDGESTONE CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3310763-B1 | AMIDINE CATALYST FOR CURABLE COMPOSITIONS | SIKA TECH AG (CH) | 2020-11-18 | — | — | EP | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| WO-2009102623-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2009102623-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090208740-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-08-20 | — | — | US | disclosed |
| US-20090208740-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-08-20 | — | — | US | disclosed |
| US-20090208740-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-08-20 | — | — | US | disclosed |
| EP-1975200-A1 | RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE | Bridgestone Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
| US-20080177017-A1 | Modified Polymer, Rubber Composition, and Tire | BRIDGESTONE CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |
| EP-1834966-A1 | MODIFIED POLYMER, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208740-A1 | ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS | AAAS, CDH1, PTK2 | THRB 4443/4885THRA 3397/4885MAPK1 704/4885 |
| US-11292771-B2 | Amidine catalyst for curable compositions | ADM2, GMNN, ARG1 | THRB 4821/4885THRA 4748/4885MAPK1 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.