SCHEMBL13327014

SCHEMBL13327014

CC1CN1CCC(=O)OCCO

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 10/20 0.42
THRA P10827 1/20 0.42
MGLL Q99685 1/20 0.36
SLC29A1 Q99808 1/20 0.36
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
DGKA P23743 1/20 0.32
DRD3 P35462 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672310 0.91 THRB (0.44) THRBTHRASLC29A1ADRA2AADRA1A
SCHEMBL13327007 0.88 THRB (0.45) THRBTHRASLC29A1MAPT
SCHEMBL16597545 0.87 THRB (0.49) THRBTHRASLC29A1ADRA2AADRA1A
SCHEMBL673561 0.86 THRB (0.48) THRBTHRASLC29A1MAPTDGKA
SCHEMBL10079025 0.86 THRB (0.51) THRBTHRASLC29A1MAPTDGKA
SCHEMBL13327010 0.84 THRB (0.41) THRBTHRASLC29A1ADRA2AADRA1A
SCHEMBL28146 0.83 THRB (0.56) THRBTHRAMAPTDGKA
SCHEMBL674504 0.81 HRH3 (0.44) THRBTHRAHRH3
SCHEMBL2354033 0.81 TSHR (0.32) THRBTHRAMGLLSLC29A1DRD3
SCHEMBL9327544 0.81 TSHR (0.43) THRBTHRASLC29A1DGKAHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283550-B1 CATALYST CONTAINING AMIDINE GROUPS SIKA TECH AG (CH) 2020-12-16 EP disclosed
CN-107428941-B Amidino group-containing catalyst SIKA技术股份公司 2020-11-24 CN disclosed
US-10392480-B2 Catalyst containing amidine groups SIKA TECHNOLOGY AG (CH) 2019-08-27 US disclosed
US-20180171082-A1 CATALYST CONTAINING AMIDINE GROUPS SIKA TECHNOLOGY AG (CH) 2018-06-21 US disclosed
US-7714076-B2 Acrylic pressure-sensitive adhesives with aziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-05-11 US disclosed
US-7714076-B2 Acrylic pressure-sensitive adhesives with aziridine crosslinking agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-05-11 US disclosed
US-20090246390-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2009-10-01 US disclosed
US-20090246390-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY 2009-10-01 US disclosed
WO-2009120420-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090246390-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS AAAS, CDH1, PTK2 THRB 4443/4885THRA 3397/4885MGLL 4263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.