Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24594401 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL21339523 | 0.93 | ALDH1A1 (0.40) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL19041078 | 0.93 | ALDH1A1 (0.40) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL24594127 | 0.93 | ALDH1A1 (0.43) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL13593603 | 0.93 | ALDH1A1 (0.43) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL12133348 | 0.92 | MEN1 (0.43) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL13644724 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL16905357 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18211417 | 0.89 | ALDH1A1 (0.38) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL16908127 | 0.88 | ALDH1A1 (0.37) | ALDH1A1CYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9139610-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150197792-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2015-07-16 | — | — | US | disclosed |
| US-9018369-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-8946404-B2 | Dark quenchers for donor-acceptor energy transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140323703-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140316118-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-10-23 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140187763-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. | 2014-07-03 | — | — | US | disclosed |
| US-8674094-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-03-18 | — | — | US | disclosed |
| US-8119781-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110178280-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-20110092679-A1 | Dark Quenchers For Donor-Acceptor Energy Transfer | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100021922-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | BIOSEARCH TECHNOLOGIES, INC. (US) | 2010-01-28 | — | — | US | disclosed |
| US-7635762-B2 | Luminescent metal ion complexes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES (US) | 2009-10-15 | — | — | US | disclosed |
| US-7582432-B2 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070154898-A1 | Multiplexing methods using dark quenchers, nonfluorescing disazo dyes, functionalized for their rapid attachment to probe components; engineered to have a desired light absorption profile; facilitate interaction between quencher and fluorophore without form nucleic acid secondary structure | BIOSEARCH TECHNOLOGIES, INC. (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178280-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | NQO1, BLVRB, SQOR | ALDH1A1 1120/4885CYP1A2 1235/4885MEN1 3888/4885 |
| US-20090259030-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ALDH1A1 1107/4885CYP1A2 4441/4885MEN1 3912/4885 |
| US-20110092679-A1 | Dark Quenchers For Donor-Acceptor Energy Transfer | NQO1, BLVRB, SQOR | ALDH1A1 1120/4885CYP1A2 1235/4885MEN1 3888/4885 |
| US-20100130733-A1 | LUMINESCENT METAL ION COMPLEXES | SLC30A6, SLC39A14, SLC39A3 | ALDH1A1 2052/4885CYP1A2 4451/4885MEN1 865/4885 |
| US-20110282041-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | DDX1, DDX18, DDX3X | ALDH1A1 1107/4885CYP1A2 4441/4885MEN1 3912/4885 |
| US-20140323703-A1 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER | NQO1, BLVRB, SQOR | ALDH1A1 1120/4885CYP1A2 1235/4885MEN1 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.