Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079264 | 0.82 | POLB (0.41) | POLBCXCR4ALDH1A1TSHRKDM1A | |
| SCHEMBL10079261 | 0.82 | PRKCQ (0.43) | PRKCQCXCR4MEN1KMT2ARAB9A | |
| SCHEMBL4920325 | 0.72 | GRIN2B (0.59) | KDM1ACARM1PRMT6MEN1KMT2A | |
| SCHEMBL1518347 | 0.72 | POLB (0.46) | POLBALDH1A1TSHRKDM1ACARM1 | |
| SCHEMBL4920332 | 0.72 | GRIN2B (0.59) | KDM1ACARM1PRMT6MEN1KMT2A | |
| SCHEMBL26268982 | 0.72 | POLB (0.62) | POLBCXCR4ALDH1A1TSHRKDM1A | |
| SCHEMBL10080416 | 0.72 | PRMT5 (0.40) | PRKCQCXCR4ALDH1A1MEN1KMT2A | |
| SCHEMBL10079265 | 0.71 | PRMT5 (0.35) | PRKCQCXCR4MEN1KMT2ARAB9A | |
| SCHEMBL10079673 | 0.71 | CXCR4 (0.51) | CXCR4ALDH1A1PRMT6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31567098 | 0.70 | POLB (0.66) | POLBCXCR4ALDH1A1TSHRKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |