Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079261 | 0.86 | PRKCQ (0.43) | PRMT5WDR77PRKCQCXCR4KMT2A | |
| SCHEMBL10079675 | 0.79 | PRMT5 (0.41) | PRMT5WDR77EPHX1 | |
| SCHEMBL10080416 | 0.79 | PRMT5 (0.40) | PRMT5WDR77PRKCQCXCR4KMT2A | |
| SCHEMBL10080359 | 0.78 | PRMT5 (0.58) | PRMT5WDR77CXCR4 | |
| SCHEMBL18096447 | 0.76 | CXCR4 (0.50) | CXCR4KMT2AMEN1HDAC6NPC1 | |
| SCHEMBL10079676 | 0.72 | LTA4H (0.37) | PRMT5WDR77CYP2D6 | |
| SCHEMBL25895829 | 0.72 | CYP2D6 (0.42) | PRKCQKMT2AMEN1CYP2D6GNRHR | |
| SCHEMBL10079262 | 0.71 | POLB (0.41) | PRKCQCXCR4KMT2AMEN1RAB9A | |
| SCHEMBL7936390 | 0.69 | HRH3 (0.42) | — | |
| SCHEMBL22183983 | 0.68 | HDAC6 (0.53) | PRMT5WDR77CXCR4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |