Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079262 | 0.82 | POLB (0.41) | POLBALDH1A1TSHRKDM1ACARM1 | |
| SCHEMBL5760854 | 0.80 | KCNH2 (0.46) | POLBALDH1A1TSHRKDM1ACARM1 | |
| SCHEMBL10080359 | 0.79 | PRMT5 (0.58) | PRMT5WDR77EP300CHRM1CHRM3 | |
| SCHEMBL1586716 | 0.79 | HRH3 (0.49) | POLBMEN1KMT2ASOS1BCHE | |
| SCHEMBL4586847 | 0.77 | CARM1 (0.56) | POLBALDH1A1CARM1PRMT6PRMT5 | |
| SCHEMBL3359770 | 0.76 | POLB (0.69) | POLBKDM1APRMT5WDR77MEN1 | |
| SCHEMBL20804080 | 0.75 | ACHE (0.49) | CARM1PRMT6MEN1KMT2ABCHE | |
| SCHEMBL3818596 | 0.72 | CCNT1 (0.41) | POLBALDH1A1TSHRCARM1PRMT6 | |
| SCHEMBL4980744 | 0.72 | PRMT5 (0.64) | POLBPRMT5WDR77HRH3PIM1 | |
| SCHEMBL26268982 | 0.72 | POLB (0.62) | POLBALDH1A1TSHRKDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |