Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 10/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080416 | 0.90 | PRMT5 (0.40) | PRKCQMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL10079265 | 0.86 | PRMT5 (0.35) | PRKCQMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL10080359 | 0.85 | PRMT5 (0.58) | PRMT5WDR77CXCR4 | |
| SCHEMBL10079262 | 0.82 | POLB (0.41) | PRKCQMEN1KMT2ACXCR4RAB9A | |
| SCHEMBL10079675 | 0.78 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL20625942 | 0.77 | HDAC6 (0.49) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL10079676 | 0.73 | LTA4H (0.37) | CYP2D6PRMT5WDR77 | |
| SCHEMBL29760365 | 0.72 | CXCR4 (0.59) | PRKCQMEN1KMT2ATP53CYP3A4 | |
| SCHEMBL22183983 | 0.72 | HDAC6 (0.53) | MEN1KMT2ATP53CYP3A4CYP2D6 | |
| SCHEMBL10079673 | 0.71 | CXCR4 (0.51) | MEN1KMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |