Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943921 | 0.90 | L3MBTL1 (0.58) | L3MBTL1CCR5ALDH1A1KDM4EGLA | |
| SCHEMBL10079673 | 0.86 | CXCR4 (0.51) | L3MBTL1PRMT6CCR5ALDH1A1KDM4E | |
| SCHEMBL31540796 | 0.84 | L3MBTL1 (0.47) | L3MBTL1CCR5ALDH1A1KDM4EGLA | |
| SCHEMBL16795119 | 0.83 | L3MBTL1 (0.46) | L3MBTL1CCR5ALDH1A1KDM4EGLA | |
| SCHEMBL1021686 | 0.78 | ALDH1A1 (0.60) | CCR5ALDH1A1KDM4ELTA4HSIGMAR1 | |
| SCHEMBL2855576 | 0.77 | SIGMAR1 (0.68) | L3MBTL1ALDH1A1KDM4EGLAGAA | |
| Hydrochloric Acid SCHEMBL11538526 | 0.76 | SIGMAR1 (0.66) | L3MBTL1ALDH1A1KDM4EGLAGAA | |
| Hydrochloric Acid SCHEMBL11533737 | 0.76 | MEN1 (0.58) | CCR5ALDH1A1KDM4ELTA4HSIGMAR1 | |
| Hydrochloric Acid SCHEMBL2673496 | 0.76 | MEN1 (0.58) | CCR5ALDH1A1KDM4ELTA4HSIGMAR1 | |
| SCHEMBL10079679 | 0.75 | CYP2D6 (0.42) | L3MBTL1PRMT6ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |