Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.58 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.58 |
| ▸ | EP300 | Q09472 | 5/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079261 | 0.85 | PRKCQ (0.43) | PRMT5WDR77CXCR4 | |
| SCHEMBL10080416 | 0.84 | PRMT5 (0.40) | PRMT5WDR77CXCR4 | |
| SCHEMBL10079675 | 0.84 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL10079264 | 0.79 | POLB (0.41) | PRMT5WDR77EP300CHRM1CXCR4 | |
| SCHEMBL10079265 | 0.78 | PRMT5 (0.35) | PRMT5WDR77CXCR4 | |
| SCHEMBL31507093 | 0.77 | PRMT5 (0.70) | PRMT5WDR77SLC2A1CXCR4CHRM2 | |
| SCHEMBL10079676 | 0.77 | LTA4H (0.37) | PRMT5WDR77 | |
| SCHEMBL6946412 | 0.70 | PRMT5 (0.60) | PRMT5WDR77CXCR4 | |
| SCHEMBL10079262 | 0.68 | POLB (0.41) | CXCR4 | |
| SCHEMBL30933697 | 0.68 | PRMT5 (0.47) | PRMT5WDR77EP300SLC2A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |