SCHEMBL10079604

SCHEMBL10079604

c1ccc(C2Oc3ccccc3C2c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 1/20 0.41
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
MAOB P27338 3/20 0.36
ACE P12821 2/20 0.36
MAOA P21397 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CYP19A1 P11511 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NR3C1 P04150 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27540720 0.86 EDNRA (0.37) EDNRAESR1ESR2ALDH1A1LMNA
SCHEMBL21946447 0.79 OPRD1 (0.37) EDNRAESR1ESR2ALDH1A1LMNA
SCHEMBL28258278 0.79 BRD4 (0.48) EDNRAALDH1A1LMNAMAPTKMT2A
SCHEMBL13991613 0.77 AHR (0.40) ESR1ESR2ALDH1A1KMT2AMEN1
SCHEMBL10068090 0.77 BRD4 (0.46) ESR1ESR2ALDH1A1LMNAMAPT
SCHEMBL18165282 0.75 ALDH1A1 (0.36) EDNRAALDH1A1LMNAMAPTKDM4E
SCHEMBL13287870 0.75 MAOB (0.38) EDNRAESR1ESR2LMNAMAPT
SCHEMBL27950503 0.75 EDNRA (0.52) EDNRAALDH1A1KMT2APTGS2BRD4
SCHEMBL1257771 0.74 MAOA (0.41) EDNRAESR1ESR2ALDH1A1LMNA
SCHEMBL2009426 0.74 ESR1 (0.36) ESR1ESR2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9832880-B2 Electronic apparatus and method for manufacturing the same Innolux Corporation (TW) 2017-11-28 US disclosed
US-9832880-B2 Electronic apparatus and method for manufacturing the same Innolux Corporation (TW) 2017-11-28 US disclosed
US-20140362545-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME Innolux Corporation (TW) 2014-12-11 US disclosed
US-20140362545-A1 ELECTRONIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME Innolux Corporation (TW) 2014-12-11 US disclosed
US-8114993-B2 Use of aryl chlorides in palladium-catalyzed C-H bond functionalization THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-02-14 US disclosed
US-20090012293-A1 USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012293-A1 USE OF ARYL CHLORIDES IN PALLADIUM-CATALYZED C-H BOND FUNCTIONALIZATION DBH, DDT, CYCS EDNRA 2989/4885ESR1 1645/4885ESR2 2864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.