Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079903 | 0.99 | HTR2C (0.47) | HTR2CSLC6A4HTR2AKMT2ACNR1 | |
| SCHEMBL10080375 | 0.97 | HTR2C (0.45) | HTR2CSLC6A4HTR2AKMT2ACACNA1B | |
| SCHEMBL10080295 | 0.94 | HTR2C (0.42) | HTR2CSLC6A4HTR2AKMT2ACNR2 | |
| SCHEMBL360796 | 0.90 | HTR2C (0.40) | HTR2CSLC6A4HTR2A | |
| SCHEMBL10080650 | 0.89 | HTR2C (0.40) | HTR2CSLC6A4HTR2AKMT2ACACNA1B | |
| SCHEMBL359860 | 0.89 | HTR2C (0.40) | HTR2CSLC6A4HTR2A | |
| SCHEMBL361219 | 0.88 | HTR2C (0.40) | HTR2CSLC6A4HTR2ACACNA1BOPRM1 | |
| SCHEMBL360372 | 0.88 | HTR2C (0.40) | HTR2CSLC6A4HTR2A | |
| SCHEMBL20662390 | 0.86 | HTR2C (0.38) | HTR2CSLC6A4HTR2AKMT2APDE4B | |
| SCHEMBL360212 | 0.85 | KMT2A (0.39) | HTR2CSLC6A4KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108494-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | NEUROINNOVATECH APS (DK) | 2026-04-23 | — | — | US | disclosed |
| US-12508244-B2 | Therapeutic agent for non-motor symptoms associated with Parkinson's disease | NEUROINNOVATECH APS (DK) | 2025-12-30 | — | — | US | disclosed |
| US-20230149357-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-18 | — | — | US | disclosed |
| US-11576897-B2 | Therapeutic agent for non-motor symptoms associated with Parkinson's disease | Sumitomo Pharma Co., Ltd. (JP) | 2023-02-14 | — | — | US | disclosed |
| US-11312688-B2 | Pyrazole compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-04-26 | — | — | US | disclosed |
| US-11312688-B2 | Pyrazole compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-04-26 | — | — | US | disclosed |
| US-20210299099-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-09-30 | — | — | US | disclosed |
| US-20200308119-A1 | PYRAZOLE COMPOUND | NEUROINNOVATECH APS (DK) | 2020-10-01 | — | — | US | disclosed |
| US-10723703-B2 | Pyrazole compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-07-28 | — | — | US | disclosed |
| EP-3569233-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2019-11-20 | — | — | EP | disclosed |
| US-20140031406-A1 | PYRAZOLE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20140031406-A1 | PYRAZOLE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| US-8569353-B2 | Pyrazole compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8569353-B2 | Pyrazole compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-8569353-B2 | Pyrazole compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2594559-A1 | PYRAZOLE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20130116296-A1 | PYRAZOLE COMPOUND | NEUROINNOVATECH APS (DK) | 2013-05-09 | — | — | US | disclosed |
| US-20130116296-A1 | PYRAZOLE COMPOUND | NEUROINNOVATECH APS (DK) | 2013-05-09 | — | — | US | disclosed |
| US-20130116296-A1 | PYRAZOLE COMPOUND | NEUROINNOVATECH APS (DK) | 2013-05-09 | — | — | US | disclosed |
| WO-2012008528-A1 | PYRAZOLE COMPOUND | 大日本住友製薬株式会社 (JP) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11576897-B2 | Therapeutic agent for non-motor symptoms associated with Parkinson's disease | PARK7, SNCA, ACHE | HTR2C 31/4885SLC6A4 16/4885HTR2A 26/4885 |
| US-11312688-B2 | Pyrazole compound | HTR2C, HTR3B, HTR3A | HTR2C 1/4885SLC6A4 22/4885HTR2A 7/4885 |
| US-20130116296-A1 | PYRAZOLE COMPOUND | HTR2C, HTR3B, HTR3A | HTR2C 1/4885SLC6A4 22/4885HTR2A 7/4885 |
| US-20200308119-A1 | PYRAZOLE COMPOUND | HTR2C, HTR3B, HTR3A | HTR2C 1/4885SLC6A4 22/4885HTR2A 7/4885 |
| US-20230149357-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | PARK7, SNCA, ACHE | HTR2C 26/4885SLC6A4 16/4885HTR2A 23/4885 |
| US-20210299099-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | PARK7, SNCA, ACHE | HTR2C 31/4885SLC6A4 16/4885HTR2A 26/4885 |
| US-20260108494-A1 | THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE | PARK7, SNCA, HTR6 | HTR2C 4/4885SLC6A4 60/4885HTR2A 16/4885 |
| US-10723703-B2 | Pyrazole compound | HTR2C, HTR3B, HTR3A | HTR2C 1/4885SLC6A4 22/4885HTR2A 7/4885 |
| US-20140031406-A1 | PYRAZOLE COMPOUND | HTR2C, HTR3B, HTR3A | HTR2C 1/4885SLC6A4 22/4885HTR2A 7/4885 |
| US-12508244-B2 | Therapeutic agent for non-motor symptoms associated with Parkinson's disease | PARK7, SNCA, HTR6 | HTR2C 5/4885SLC6A4 78/4885HTR2A 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.