Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 4/20 | 0.51 |
| ▸ | YAP1 | P46937 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083011 | 0.85 | ACE (0.61) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL26195395 | 0.81 | MDM4 (0.52) | ADORA3ADORA2AADORA2BADORA1PIN1 | |
| SCHEMBL7329010 | 0.79 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL8648996 | 0.79 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL8648992 | 0.79 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL10071091 | 0.79 | ACE (0.57) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL26195412 | 0.79 | MDM4 (0.51) | ADORA3ADORA2AADORA2BADORA1PIN1 | |
| SCHEMBL8647459 | 0.77 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL8647455 | 0.77 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1ACE | |
| SCHEMBL7269454 | 0.77 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | BRACCO IMAGING SPA (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045393-A1 | LHRH-II PEPTIDE ANALOGS | LHCGR, GNRHR, FSHR | ADORA3 3804/4885ADORA2A 4476/4885ADORA2B 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.