Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071201 | 0.96 | FTO (0.47) | PDK2JAK2FTOHDAC6MMP14 | |
| SCHEMBL10082966 | 0.91 | PDK2 (0.40) | PDK2JAK2FTOMMP14NT5E | |
| SCHEMBL10071204 | 0.88 | FTO (0.57) | PDK2JAK2FTOHDAC6NT5E | |
| SCHEMBL28607477 | 0.84 | FTO (0.53) | PDK2JAK2FTOHDAC6MMP14 | |
| SCHEMBL23062999 | 0.83 | FTO (0.50) | PDK2FTOMEN1MAPTHPGD | |
| SCHEMBL20841462 | 0.80 | PDK2 (0.47) | PDK2JAK2FTOHDAC6NT5E | |
| SCHEMBL10071136 | 0.79 | ALB (0.39) | PDK2JAK2FTOHDAC6MMP14 | |
| SCHEMBL10071199 | 0.79 | FTO (0.56) | PDK2FTOHDAC6MEN1MAPT | |
| SCHEMBL10071137 | 0.79 | FTO (0.37) | PDK2JAK2FTOMMP14NT5E | |
| SCHEMBL10082951 | 0.79 | PDK2 (0.43) | PDK2JAK2HDAC6MMP14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | AAT BIOQUEST, INC. | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | PHYKPL, PFAS, PHOSPHO1 | PDK2 3930/4885JAK2 3553/4885FTO 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.