Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083040 | 0.91 | PDK2 (0.48) | PDK2MEN1MAPTHTTKMT2A | |
| SCHEMBL10071201 | 0.88 | FTO (0.47) | PDK2MAPTJAK2MMP14FTO | |
| SCHEMBL6879196 | 0.86 | GSTP1 (0.50) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10071154 | 0.84 | JAK2 (0.35) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL23758534 | 0.82 | GSTP1 (0.44) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10138035 | 0.81 | ITPR3 (0.43) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10082962 | 0.81 | FTO (0.48) | MEN1USP2ALDH1A1LMNAMAPT | |
| SCHEMBL12563930 | 0.80 | MEN1 (0.52) | PDK2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL10071204 | 0.80 | FTO (0.57) | PDK2JAK2FTONT5ENAALAD2 | |
| SCHEMBL28607477 | 0.78 | FTO (0.53) | PDK2MEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | AAT BIOQUEST, INC. | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016128-A1 | Rhodamine lactone phosphoramidites and polymers | PHYKPL, PFAS, PHOSPHO1 | PDK2 3930/4885MEN1 3312/4885USP2 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.