Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 13/20 | 0.46 |
| ▸ | MAOB | P27338 | 13/20 | 0.46 |
| ▸ | KDM1A | O60341 | 11/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15767768 | 0.86 | GAA (0.53) | MAOAMAOBKDM1A | |
| SCHEMBL903428 | 0.86 | GAA (0.53) | MAOAMAOBKDM1A | |
| Trifluoroacetic Acid SCHEMBL15667517 | 0.79 | GAA (0.47) | MAOAMAOBKDM1A | |
| SCHEMBL903571 | 0.79 | MAOA (0.50) | MAOAMAOBKDM1ATDP1L3MBTL1 | |
| SCHEMBL2074431 | 0.78 | KDM1A (0.50) | MAOAMAOBKDM1A | |
| SCHEMBL2074430 | 0.78 | KDM1A (0.50) | MAOAMAOBKDM1A | |
| SCHEMBL10083061 | 0.77 | PPARG (0.43) | PPARGTSHRTDP1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2131519 | 0.77 | KDM1A (0.51) | MAOAMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL2130468 | 0.77 | KDM1A (0.51) | MAOAMAOBKDM1A | |
| Trifluoroacetic Acid SCHEMBL15284412 | 0.76 | GAA (0.47) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | PPOX, IDH3A, HMOX2 | PPARG 1579/4885MAOA 458/4885MAOB 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.