Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544674 | 0.87 | SMN1; SMN2 (0.52) | TSHRL3MBTL1GAASMN1; SMN2CACNA1F | |
| SCHEMBL545342 | 0.80 | KMT2A (0.43) | GAASMN1; SMN2MAPK1ALDH1A1AURKA | |
| SCHEMBL10083062 | 0.77 | PPARG (0.46) | PPARGTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL545242 | 0.76 | CACNA1F (0.44) | TSHRGAASMN1; SMN2CACNA1FCACNA1D | |
| SCHEMBL545135 | 0.75 | CYP2C19 (0.43) | GAASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL16482743 | 0.75 | SIGMAR1 (0.39) | PPARGTSHRTDP1L3MBTL1CACNA1F | |
| SCHEMBL544636 | 0.75 | GAA (0.42) | GAASMN1; SMN2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL544761 | 0.75 | OPRK1 (0.45) | GAASMN1; SMN2CACNA1DCYP3A4 | |
| SCHEMBL544647 | 0.75 | CACNA1C (0.57) | TSHRCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL544900 | 0.72 | CA1 (0.42) | TSHRL3MBTL1GAASMN1; SMN2CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | PPOX, IDH3A, HMOX2 | PPARG 1579/4885TSHR 4237/4885TDP1 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.