Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.75 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.75 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.75 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632145 | 0.87 | ADORA3 (0.74) | ADORA3F2NPC1RAB9ATP53 | |
| SCHEMBL10084523 | 0.84 | KMT2A (0.70) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL822127 | 0.81 | ADORA3 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3ADORA3 | |
| SCHEMBL10068146 | 0.78 | ADORA3 (0.63) | ADORA3F2NPC1RAB9ATP53 | |
| SCHEMBL4116110 | 0.78 | CACNA1G (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL10082863 | 0.78 | FPR2 (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL3111821 | 0.76 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL6647475 | 0.76 | SMN1; SMN2 (0.58) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 | |
| SCHEMBL10759295 | 0.75 | DEGS1 (0.51) | CHRNB2CHRNA4CHRNB4CHRNA3ADORA3 | |
| SCHEMBL13779848 | 0.75 | RXFP1 (0.65) | CHRNB2CHRNA4CHRNB4CHRNA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | CHRNB2 4648/4885CHRNA4 4289/4885CHRNB4 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.