Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.58 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.58 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL7940849 | 0.95 | CHRM5 (0.53) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Acrylic Acid SCHEMBL3223308 | 0.94 | CHRM5 (0.51) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL134541 | 0.93 | CHRM5 (0.57) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL25422044 | 0.91 | TSHR (0.56) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL20908 | 0.91 | TSHR (0.56) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL27681180 | 0.89 | CHRM5 (0.53) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Fluoride Ion SCHEMBL1254299 | 0.89 | TSHR (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL1703727 | 0.89 | TSHR (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL28367647 | 0.89 | TSHR (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL15738807 | 0.89 | TSHR (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005175-B | Fracturing flowback fluid treatment method and device for high-alkalinity oil field | 克拉玛依市三达新技术股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118005175-A | Fracturing flowback fluid treatment method and device for high-alkalinity oil field | 克拉玛依市三达新技术股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-110105938-B | High-strength slow-crosslinking chromium jelly and preparation method thereof | 中国石油大学(华东) | 2020-09-29 | — | — | CN | claimed |
| CN-110959038-A | Enzyme products | C-乐克塔股份有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-3625334-A1 | ENZYME PRODUCTS | c-LEcta GmbH (DE) | 2020-03-25 | — | — | EP | claimed |
| WO-2018210794-A1 | ENZYME PRODUCTS | C-LECTA GMBH (DE) | 2018-11-22 | — | — | WO | claimed |
| US-8318616-B2 | Salt water swellable compositions and articles | AMCOL INTERNATIONAL CORPORATION (US) | 2012-11-27 | — | — | US | claimed |
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | L'OREAL S.A. (FR) | 2007-10-25 | — | — | US | claimed |
| EP-0604153-B1 | Process for preparing high solids non-aqueous polymer compositions | CALGON CORP (US) | 1998-02-04 | — | — | EP | claimed |
| US-20260008955-A1 | SUBTERRANEAN FORMATIONS | INDEPENDENCE OILFIELD CHEMICALS LLC (US) | 2026-01-08 | — | — | US | disclosed |
| US-20240368462-A1 | SUBTERRANEAN FORMATIONS | INDEPENDENCE OILFIELD CHEMICALS LLC | 2024-11-07 | — | — | US | disclosed |
| CN-118005175-B | Fracturing flowback fluid treatment method and device for high-alkalinity oil field | 克拉玛依市三达新技术股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118005175-A | Fracturing flowback fluid treatment method and device for high-alkalinity oil field | 克拉玛依市三达新技术股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-114479008-B | Demulsifier and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-5643461-A | RELEASE AGENTS FOR WATER USING CATIONIC WATER SOLUBLE CATIONIC POLYMERS, MIXING WITH BRANCHING AGENT THEN DEWATERING | CYTEC TECHNOLOGY CORP. (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0730618-A1 | MULTIMODAL EMULSIONS AND PROCESSES FOR PREPARING MULTIMODAL EMULSIONS | CYTEC TECHNOLOGY CORP. (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0728705-A2 | Method for using novel high solids polymer compositions as flocculation acids | CALGON CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995014728-A1 | MULTIMODAL EMULSIONS AND PROCESSES FOR PREPARING MULTIMODAL EMULSIONS | CYTEC TECHNOLOGY CORP. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-5405554-A | Water in oil emulsion containing cationic polymers | CYTEC TECHNOLOGY CORP. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0277728-A2 | Drainage and retention aids for newsprint furnishes | CALGON CORPORATION (US) | 1988-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | CUTA, TYR, PRKDC | CHRM1 755/4885CHRM3 1174/4885CHRM2 703/4885 |
| US-20260008955-A1 | SUBTERRANEAN FORMATIONS | TAF1, TAF9, TST | CHRM1 3900/4885CHRM3 3525/4885CHRM2 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.