Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GCK | P35557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873516 | 0.88 | MAPK1 (0.56) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL10084297 | 0.88 | TSHR (0.52) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL9153870 | 0.87 | MAPK1 (0.55) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL4832627 | 0.87 | ALDH1A1 (0.59) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL27730232 | 0.87 | MAPK1 (0.55) | SMN1; SMN2MAPK1NPC1RAB9ALMNA | |
| SCHEMBL27751166 | 0.87 | LMNA (0.69) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL10349418 | 0.86 | TP53 (0.56) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL15331063 | 0.85 | MAPK1 (0.53) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL5835447 | 0.83 | MAPK1 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AMAPT | |
| SCHEMBL91510 | 0.83 | MEN1 (0.53) | SMN1; SMN2MAPK1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | SMN1; SMN2 4328/4885MAPK1 2690/4885NPC1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.