Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873516 | 0.88 | MAPK1 (0.56) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL9153870 | 0.87 | MAPK1 (0.55) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL4832627 | 0.87 | ALDH1A1 (0.59) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL10084516 | 0.87 | SMN1; SMN2 (0.62) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL15331063 | 0.85 | MAPK1 (0.53) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL10349418 | 0.84 | TP53 (0.56) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL27751166 | 0.82 | LMNA (0.69) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL4873462 | 0.81 | AOC3 (0.55) | MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27523268 | 0.81 | MAPK1 (0.54) | MAPK1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8872595 | 0.81 | ELOVL1 (0.66) | NPC1RAB9AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101362735-B | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICALS CO LTD | 2011-01-05 | — | — | CN | disclosed |
| CN-101362735-A | Preparation method of ethyl 2-[[(bezyloxy)carbonyl]amido]-4-thiazolyl acetate | SHANDONG JINCHENG PHARMACEUTIC (CN) | 2009-02-11 | — | — | CN | disclosed |