SCHEMBL10085512

SCHEMBL10085512

CCCCOc1ccc(CC(CO)NC(=O)[C@@H](NC(=O)CCCCCCC(=O)OC)C(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.51
ITGA2B P08514 2/20 0.51
CNR1 P21554 2/20 0.47
LPAR3 Q9UBY5 9/20 0.47
CNR2 P34972 2/20 0.46
PPARG P37231 1/20 0.45
ACACB O00763 1/20 0.45
LPAR1 Q92633 2/20 0.44
ENPP2 Q13822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622370 0.88 LPAR3 (0.53) LPAR3LPAR1ENPP2
SCHEMBL623511 0.87 CNR1 (0.53) CNR1
SCHEMBL623185 0.86 CYP3A4 (0.54) CNR1
SCHEMBL10085515 0.86 ITGB3 (0.50) ITGB3ITGA2BLPAR3PPARGACACB
SCHEMBL10084886 0.85 ITGB3 (0.48) ITGB3ITGA2BLPAR3PPARGACACB
SCHEMBL10084883 0.77 ITGB3 (0.51) ITGB3ITGA2B
SCHEMBL623355 0.76 ITGB3 (0.39) ITGB3ITGA2BLPAR3ACACBENPP2
SCHEMBL622452 0.75 CASP1 (0.45) CNR1
SCHEMBL623001 0.74 CTSB (0.50) LPAR3LPAR1ENPP2
SCHEMBL10084885 0.74 CASP1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012021788-A2 DIPEPTIDE CALPAIN INHIBITORS BANYAN BIOMARKERS (US) 2012-02-16 WO disclosed