SCHEMBL1008743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28024938	0.86	PRMT5 (0.42)	CYP2C19PRMT5WDR77CDK8PTGS1
	SCHEMBL18421684	0.85	PRMT5 (0.41)	ALOX15ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL17116599	0.85	PRMT5 (0.47)	PRMT5WDR77CLK4GSK3BGRM5
	SCHEMBL17116282	0.84	PRMT5 (0.43)	ALOX15ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL18462115	0.84	PRMT5 (0.44)	ALOX15ALDH1A1PRMT5WDR77LRRK2
	SCHEMBL14735824	0.83	CYP11B2 (0.51)	ALOX15ALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL3711809	0.83	KDM4E (0.45)	ALDH1A1MEN1KMT2ACYP1A2PRMT5
	SCHEMBL17116724	0.83	PRMT5 (0.43)	ALOX15PRMT5WDR77CLK4GSK3B
	SCHEMBL22290166	0.83	ERBB2 (0.45)	ALDH1A1MEN1KMT2APRMT5WDR77
	SCHEMBL17117023	0.83	PRMT5 (0.46)	ALOX15ALDH1A1PRMT5WDR77CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.