Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008743 | 0.86 | ALOX15 (0.44) | PRMT5WDR77CYP11B1GRM5PTGS1 | |
| SCHEMBL18421684 | 0.83 | PRMT5 (0.41) | PRMT5WDR77CYP11B1CYP11B2GRM5 | |
| SCHEMBL17116599 | 0.83 | PRMT5 (0.47) | PRMT5WDR77CYP11B1SQORCYP11B2 | |
| SCHEMBL7679638 | 0.81 | ERBB2 (0.45) | PRMT5WDR77CYP11B2GRM5KDM4E | |
| SCHEMBL17116724 | 0.81 | PRMT5 (0.43) | PRMT5WDR77CYP11B1SQORCYP11B2 | |
| SCHEMBL3711809 | 0.81 | KDM4E (0.45) | PRMT5WDR77SQORCYP11B2LMNA | |
| SCHEMBL29883865 | 0.81 | CYP11B2 (0.51) | CYP11B1CYP11B2CYP19A1LMNAKDM4E | |
| SCHEMBL14735824 | 0.81 | CYP11B2 (0.51) | CYP11B1CYP11B2CYP19A1LMNAKDM4E | |
| SCHEMBL22290166 | 0.81 | ERBB2 (0.45) | PRMT5WDR77CYP11B1CYP11B2GRM5 | |
| SCHEMBL2474360 | 0.81 | ESR2 (0.53) | PRMT5WDR77CYP11B2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755471-A | Pyridine derivative and drug | NIPPON SHINYAKU CO LTD | 2015-07-01 | — | — | CN | disclosed |