Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337049 | 0.77 | MEN1 (0.42) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL6859755 | 0.75 | MEN1 (0.48) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL4012647 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AGAAKDRSMN1; SMN2 | |
| SCHEMBL14776020 | 0.74 | GOT1 (0.48) | — | |
| SCHEMBL21206275 | 0.74 | ALDH1A1 (0.37) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL29287405 | 0.73 | RAB9A (0.58) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL825684 | 0.72 | CYP1A2 (0.38) | NPC1GAAALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL23576355 | 0.71 | MEN1 (0.40) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL14776046 | 0.69 | — | — | |
| SCHEMBL7484183 | 0.68 | MEN1 (0.45) | MEN1KMT2AMAPK10GFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745067-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AG (DE) | 1996-12-04 | — | — | EP | claimed |
| WO-1995022530-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-24 | — | — | WO | claimed |
| US-8629273-B2 | Diazinylpyrazolyl compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| EP-2125789-B1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2275422-A1 | Pyrimidinylpyrazoles as insecticide and parasiticide agents | Bayer CropScience AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2125789-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077483-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2008-07-03 | — | — | WO | disclosed |
| US-5849778-A | N-pyrazolyl anilines as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5849778-A | N-pyrazolyl anilines as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0745067-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| EP-0745067-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AG (DE) | 1996-12-04 | — | — | EP | disclosed |
| WO-1995022530-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-24 | — | — | WO | disclosed |
| WO-1995022530-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | PIR, ITPA, DDT | MEN1 3897/4885KMT2A 2153/4885MAPK10 4625/4885 |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | DDT, PDHX, RECQL | MEN1 1338/4885KMT2A 2651/4885MAPK10 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.