Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569077 | 0.84 | SLC6A2 (0.46) | CTSDSLC6A2 | |
| SCHEMBL28202357 | 0.81 | ALDH1A1 (0.40) | CYP1A2ALDH1A1CYP19A1MAPK1GAA | |
| SCHEMBL28065822 | 0.79 | MAP4K4 (0.42) | CYP1A2ALDH1A1GAANPC1LMNA | |
| SCHEMBL1009812 | 0.78 | ALDH1A1 (0.44) | CYP1A2TDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL23794878 | 0.77 | KDM1A (0.38) | CYP1A2ALDH1A1TSHRHTR2BIDO1 | |
| Maleic Acid SCHEMBL10568944 | 0.75 | SLC6A2 (0.57) | ALDH1A1SLC6A2 | |
| Fumaric Acid SCHEMBL10568948 | 0.75 | SLC6A2 (0.57) | ALDH1A1SLC6A2 | |
| SCHEMBL2359099 | 0.74 | CYP19A1 (0.41) | CYP1A2TDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL4593306 | 0.73 | LMNA (0.52) | TDP1ALDH1A1L3MBTL1IDO1GAA | |
| SCHEMBL1008764 | 0.72 | MEN1 (0.45) | CYP1A2ALDH1A1HSD17B10GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | claimed |
| EP-0618904-B1 | NOVEL N-PHENYL AMINO PYRAZOLE DERIVATIVES AND MEANS AND PROCESS FOR COLOURING HAIR | WELLA AG (DE) | 1999-04-14 | — | — | EP | claimed |
| EP-0745067-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AG (DE) | 1996-12-04 | — | — | EP | claimed |
| WO-1995022530-A1 | N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-24 | — | — | WO | claimed |
| US-5430159-A | N-phenylaminopyrazole derivatives as well as composition and process for the dyeing of hair | WELLA AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | claimed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | claimed |
| JP-8208620-A | — | — | None | — | — | JP | disclosed |
| EP-4477271-B1 | N-(PHENYL)-5-(HETEROARYL)-1H-PYRAZOL-3-AMINE DERIVATIVES AS TNIK INHIBITORS FOR USE IN THE TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2026-05-13 | — | — | EP | disclosed |
| CN-114394967-B | Method for synthesizing pyrazoloquinoline derivative from 2-pyrazolyl aniline and 1, 3-dicarbonyl compound | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2023-12-15 | — | — | CN | disclosed |
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-114213412-B | Method for synthesizing pyrazoloquinoline compound from 2-pyrazoloaniline derivative and ether under acid catalysis | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2022-12-30 | — | — | CN | disclosed |
| CN-114213412-A | Method for synthesizing pyrazoloquinoline compound from 2-pyrazoloaniline derivative and ether under acid catalysis | 宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室） | 2022-03-22 | — | — | CN | disclosed |
| EP-0269806-B1 | PHENYLPYRAZOLE CARBONIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS PLANT GROWTH REGULATORS AND ANTIDOTES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |
| EP-0269806-A1 | Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-08 | — | — | EP | disclosed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | disclosed |
| US-4317823-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-02 | — | — | US | disclosed |
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | disclosed |
| US-4045428-A | Water-soluble reactive naphthylazonaphthyl dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |