SCHEMBL1008804

SCHEMBL1008804

C=C(C)C(=O)OCCNC([O])=O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.48
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ACHE P22303 8/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9087619 0.89 TSHR (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13872030 0.86 THRB (0.53) THRBTSHRALDH1A1ACHE
SCHEMBL2403793 0.86 THRB (0.53) THRBTSHRALDH1A1ACHE
SCHEMBL12808628 0.86 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16309318 0.86 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL685408 0.86 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2195083 0.86 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL85836 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14345594 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL194228 0.84 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104684944-B Polymerizable liquid crystal compound, liquid-crystal composition, macromolecular material and its manufacture method, film, Polarizer and liquid crystal indicator 富士胶片株式会社 2017-03-08 CN claimed
US-9464228-B2 Liquid crystal composition, method for manufacturing the same, and film FUJIFILM CORPORATION (JP) 2016-10-11 US claimed
CN-104662127-B Liquid-crystal composition and manufacture method, film, Polarizer and liquid crystal indicator FUJIFILM CORP. (JP) 2016-02-24 CN claimed
CN-105247012-A Polymerizable liquid crystal compound, liquid crystal composition, polymer material and production method for same, film, polarizing plate, and liquid crystal display device FUJIFILM CORP 2016-01-13 CN claimed
US-20150344782-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-12-03 US claimed
US-20150191652-A1 LIQUID CRYSTAL COMPOSITION, METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US claimed
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM FUJIFILM CORPORATION (JP) 2015-07-09 US claimed
CN-104684944-A Polymerizable liquid crystal compound, liquid crystal composition, polymer material, method for producing polymer material, and film FUJIFILM CORP 2015-06-03 CN claimed
CN-104662127-A Liquid crystal composition, method for producing same, and film FUJIFILM CORP 2015-05-27 CN claimed
US-20090191398-A1 MEMBRANES COMPRISING HYDROPHILIC COATINGS GENERAL ELECTRIC COMPANY (US) 2009-07-30 US claimed
CN-115079329-B Cholesteric liquid crystal layer, optically anisotropic body, and reflective layer 富士胶片株式会社 2024-04-19 CN disclosed
CN-116829995-A Liquid crystal composition, cured film, polarizing plate, and image display device 富士胶片株式会社 2023-09-29 CN disclosed
US-11762201-B2 Wearable display device FUJIFILM CORPORATION (JP) 2023-09-19 US disclosed
US-11732194-B2 Cholesteric liquid crystal layer, laminate, optically anisotropic body, reflective film, method for producing cholesteric liquid crystal layer, anti-counterfeit medium, and determination method FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-11693278-B2 Liquid crystal diffraction element and method for producing liquid crystal diffraction element FUJIFILM CORPORATION (JP) 2023-07-04 US disclosed
EP-1869140-A1 OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS Johnson and Johnson Vision Care, Inc. (US) 2007-12-26 EP disclosed
WO-2006110513-A1 OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-10-19 WO disclosed
WO-2006110221-A1 PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME TRANSITIONS OPTICAL, INC. (US) 2006-10-19 WO disclosed
US-20060226402-A1 Ophthalmic devices comprising photochromic materials having extended PI-conjugated systems KIM BEON-KYU 2006-10-12 US disclosed
US-20060228557-A1 Photochromic materials having extended pi-conjugated systems and compositions and articles including the same TRANSITIONS OPTICAL, INC. 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060228557-A1 Photochromic materials having extended pi-conjugated systems and compositions and articles including the same INCENP, PCNA, INTS6 THRB 4882/4885TSHR 4793/4885ALDH1A1 2220/4885
US-20150191651-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL AND METHOD FOR MANUFACTURING THE SAME, AND FILM PYM1, C9, LANCL2 THRB 4118/4885TSHR 4393/4885ALDH1A1 1441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.