Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984891 | 0.93 | THRB (0.46) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL10093531 | 0.91 | THRB (0.49) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL12358264 | 0.90 | THRB (0.61) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL10093548 | 0.89 | TSHR (0.46) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL2720435 | 0.88 | TSHR (0.56) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL10093528 | 0.88 | KDM4E (0.52) | THRBTSHRMAPK1KDM4EHIF1A | |
| SCHEMBL12808628 | 0.88 | THRB (0.52) | THRBTSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL16309318 | 0.88 | THRB (0.52) | THRBTSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL2195083 | 0.88 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Naphthalene SCHEMBL21246707 | 0.87 | MTNR1A (0.51) | THRBTSHRALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4327513-A | — | — | None | — | — | JP | disclosed |
| WO-2024203572-A1 | COPOLYMER AND CONTACT LENS TREATMENT SOLUTION | 日油株式会社 | 2024-10-03 | — | — | WO | disclosed |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| EP-2608767-B1 | POLYMER COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2023-07-26 | — | — | EP | disclosed |
| US-20230159753-A1 | POLYROTAXANE ADDITIVES FOR RIGID POLYMERS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159753-A1 | POLYROTAXANE ADDITIVES FOR RIGID POLYMERS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2023-05-25 | — | — | US | disclosed |
| EP-3402544-B1 | BIOCOMPATIBLE POLYSACCHARIDE HYDROGELS AND METHODS OF USAGE | SUN GUOMING (US) | 2022-12-07 | — | — | EP | disclosed |
| US-20220220308-A1 | POLYAMIDE-IMIDE BLOCK COPOLYMERS, PREPARATION METHOD THEREOF AND POLYAMIDE-IMIDE FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2022-07-14 | — | — | US | disclosed |
| US-20220220262-A1 | FLUORINE-CONTAINING CURABLE COMPOSITION AND ARTICLE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-07-14 | — | — | US | disclosed |
| US-20220125687-A1 | DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-04-28 | — | — | US | disclosed |
| EP-1864777-A1 | Structuring hydrogels | DWI an der RWTH Aachen e.V. (DE) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007128051-A1 | BIOLOGICAL POLYSILOXANES | VISION CRC LIMITED (AU) | 2007-11-15 | — | — | WO | disclosed |
| US-20070160838-A1 | Stabilized semiconductor nanocrystals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070160838-A1 | Stabilized semiconductor nanocrystals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-12 | — | — | US | disclosed |
| US-7160613-B2 | Stabilized semiconductor nanocrystals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160613-B2 | Stabilized semiconductor nanocrystals | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-09 | — | — | US | disclosed |
| US-5780559-A | CLEAR COATS | PPG INDUSTRIES, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998003599-A1 | CURABLE FILM-FORMING COMPOSITIONS CONTAINING AMIDE FUNCTIONAL POLYMERS | PPG INDUSTRIES, INC. (US) | 1998-01-29 | — | — | WO | disclosed |
| US-5300537-A | Bonding dental fillings | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| JP-H04327513-A | COMPOUND CAPABLE OF PROMOTING DENTIN ADHESION, PRETREATING AGENT AND BONDING COMPOSITION CONTAINING THE SAME | TERUMO CORP | 1992-11-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | PAM, CAD, FHIT | THRB 873/4885TSHR 2948/4885ALDH1A1 1173/4885 |
| US-20220125687-A1 | DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER | EPN1, ARCN1, RARA | THRB 4179/4885TSHR 3320/4885ALDH1A1 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.