Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379248 | 0.93 | EPHX2 (0.39) | EPHX2PPARGNR3C1MEN1KMT2A | |
| SCHEMBL379249 | 0.86 | MAPT (0.36) | EPHX2PPARGNR3C1MEN1KMT2A | |
| SCHEMBL8253229 | 0.72 | MAPT (0.44) | EPHX2PPARGMEN1KMT2AGAA | |
| SCHEMBL7212419 | 0.72 | PIN1 (0.46) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL5643829 | 0.71 | NR3C1 (0.44) | NR3C1FFAR1FFAR4 | |
| SCHEMBL3377851 | 0.70 | CYP1A2 (0.39) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL14489353 | 0.70 | MAPT (0.40) | PPARGNR3C1MEN1KMT2AGAA | |
| SCHEMBL379397 | 0.69 | NR3C1 (0.47) | NR3C1FFAR1FFAR4 | |
| SCHEMBL14340596 | 0.68 | NR3C1 (0.52) | NR3C1NPSR1ALDH1A1POLB | |
| SCHEMBL12834754 | 0.68 | MAPT (0.38) | EPHX2PPARGMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280974-B1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INT (DE) | 2012-01-25 | — | — | EP | disclosed |