Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15218247 | 0.77 | MEN1 (0.38) | MAPK1MEN1LMNAKMT2A | |
| SCHEMBL15218248 | 0.74 | MEN1 (0.40) | MEN1LMNAKMT2A | |
| SCHEMBL24065843 | 0.69 | LMNA (0.43) | TSHRMEN1LMNAKMT2A | |
| SCHEMBL10089427 | 0.66 | ALDH1A1 (0.37) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL25188962 | 0.65 | NPC1 (0.43) | LMNAKMT2A | |
| SCHEMBL28056762 | 0.64 | SIGMAR1 (0.46) | MEN1KMT2A | |
| SCHEMBL15956068 | 0.61 | ALDH1A1 (0.43) | TSHRMEN1LMNAKMT2A | |
| SCHEMBL15955791 | 0.61 | MGLL (0.44) | MEN1LMNAKMT2A | |
| SCHEMBL15956109 | 0.61 | MGLL (0.42) | — | |
| SCHEMBL5606199 | 0.61 | TMEM97 (0.48) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027717-A2 | FLOURESCENCE LABELING REAGENTS AND USES THEREOF | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-03-01 | — | — | WO | disclosed |