Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339301 | 0.86 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1GLAHPGDALOX12 | |
| SCHEMBL5913295 | 0.81 | NPC1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29989715 | 0.81 | NPC1 (0.57) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL98541 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1GLAHPGDALOX12 | |
| SCHEMBL10409077 | 0.79 | CYP1A2 (0.56) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7641978 | 0.79 | CNR1 (0.41) | SMN1; SMN2ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL113771 | 0.78 | ALDH1A1 (0.66) | SMN1; SMN2ALDH1A1GLAHPGDALOX12 | |
| SCHEMBL5855895 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1GLAHPGDALOX12 | |
| SCHEMBL7842965 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL7337882 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1GLAHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072734-B2 | Quaternary ammonium salt compounds | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | TEIJIN PHARMA LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | ADRB2, AGTR2, ADRB3 | SMN1; SMN2 3566/4885ALDH1A1 1896/4885GLA 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.