Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.72 |
| ▸ | LMNA | P02545 | 9/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | PKM | P14618 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | ESR1 | P03372 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 3/20 | 0.72 |
| ▸ | APEX1 | P27695 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.72 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090761 | 0.84 | SMN1; SMN2 (0.86) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL2015803 | 0.83 | ALDH1A1 (1.00) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090672 | 0.80 | TSHR (1.00) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090710 | 0.80 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090713 | 0.80 | TSHR (0.76) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090728 | 0.79 | SMN1; SMN2 (0.75) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090741 | 0.78 | HTT (0.79) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL16217081 | 0.77 | TSHR (0.78) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090735 | 0.77 | TSHR (0.71) | SMN1; SMN2LMNAALDH1A1PKMPOLB | |
| SCHEMBL10090760 | 0.73 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2016-06-16 | — | — | US | disclosed |
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2012027392-A2 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | SMN1; SMN2 4322/4885LMNA 3658/4885ALDH1A1 855/4885 |
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | SMN1; SMN2 4322/4885LMNA 3658/4885ALDH1A1 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.