SCHEMBL10092015

SCHEMBL10092015

C=C1CSCC(OC(=O)c2ccccc2)COC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
PTPN1 P18031 6/20 0.40
PTPN2 P17706 4/20 0.40
PTPRF P10586 1/20 0.40
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
PTPN6 P29350 2/20 0.38
PTPN11 Q06124 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10092123 0.86 PTPN1 (0.38) CHRNA7PTPN1PTPN2PTPRFPTPN6
SCHEMBL10092005 0.79 CHRNA7 (0.48) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL2302942 0.72 PTPN1 (0.69) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL5582384 0.72 CHRNA7 (0.49) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL2696973 0.72 CHRNA7 (0.49) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL27598256 0.72 CHRNA7 (0.49) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL10092009 0.71 PTPN1 (0.54) CHRNA7PTPN1PTPN2PTPRFPTPN6
SCHEMBL10092104 0.70 CHRNA7 (0.38) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL29804712 0.70 CHRNA7 (0.54) CHRNA7MEN1KMT2AGAAPTPN1
SCHEMBL28339381 0.69 CHRNA7 (0.56) CHRNA7MEN1KMT2AGAAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
EP-2065890-B1 Optical recording composition and holographic recording medium FUJIFILM CORP (JP) 2012-01-25 EP disclosed
US-20100241225-A1 CURABLE RESIN COMPOSITION FOR INTRAOCULAR LENS, INTRACULAR LENS MATERIAL AND INTRACULAR LENS FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-20100241225-A1 CURABLE RESIN COMPOSITION FOR INTRAOCULAR LENS, INTRACULAR LENS MATERIAL AND INTRACULAR LENS FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
EP-2065890-A2 Optical recording composition and holographic recording medium FUJIFILM Corporation (JP) 2009-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM CACNA1S, CACNA1E, CRY1 CHRNA7 406/4885MEN1 1298/4885KMT2A 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.