SCHEMBL10092123

SCHEMBL10092123

C=C1CCCC(OC(=O)c2ccc(C(=O)OC3COC(=O)C(=C)CSC3)cc2)COC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.38
PTPN2 P17706 5/20 0.38
PTPRF P10586 1/20 0.38
PTPN6 P29350 2/20 0.35
PTPN11 Q06124 2/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HTT P42858 2/20 0.35
STS P08842 4/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
TSHR P16473 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10092015 0.86 CHRNA7 (0.41) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092009 0.69 PTPN1 (0.54) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092005 0.66 CHRNA7 (0.48) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092004 0.64 PTPN1 (0.68) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL10092182 0.64 PTPN1 (0.48) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL1976081 0.64 STS (0.62) PTPN1PTPN2PTPRFSMN1; SMN2NPC1
SCHEMBL1899821 0.63 PTPN1 (0.40) PTPN1PTPN2PTPRFPTPN6PTPN11
SCHEMBL6399730 0.63 MEN1 (0.56) SMN1; SMN2STSLMNAMAPTNPSR1
SCHEMBL110657 0.62 SMN1; SMN2 (0.68) PTPN1PTPN2PTPRFSMN1; SMN2NPC1
SCHEMBL14039909 0.61 PTPN1 (0.53) PTPN1PTPN2PTPRFPTPN6PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120019938-A1 CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
EP-2065890-B1 Optical recording composition and holographic recording medium FUJIFILM CORP (JP) 2012-01-25 EP disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2009-06-04 US disclosed
EP-2065890-A2 Optical recording composition and holographic recording medium FUJIFILM Corporation (JP) 2009-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142671-A1 OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM CACNA1S, CACNA1E, CRY1 PTPN1 2628/4885PTPN2 3341/4885PTPRF 4185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.