SCHEMBL5744049

SCHEMBL5744049

Nc1ccc(C(=O)c2ccc(C#Cc3ccccc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.69
▸ APP P05067 3/20 0.54
▸ PBRM1 Q86U86 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ FFAR1 O14842 4/20 0.47
▸ SRD5A2 P31213 1/20 0.47
▸ GRM5 P41594 2/20 0.46
▸ NPC1 O15118 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ FFAR4 Q5NUL3 1/20 0.44
▸ PTGES O14684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837213 0.90 MAPT (0.56) MAPTAPPALDH1A1FFAR1SRD5A2
SCHEMBL1744898 0.88 ALDH1A1 (0.64) MAPTAPPALDH1A1MEN1KMT2A
SCHEMBL84251 0.87 PBRM1 (0.53) MAPTAPPPBRM1ALDH1A1FFAR1
SCHEMBL8837231 0.84 PBRM1 (0.74) MAPTPBRM1ALDH1A1MEN1KMT2A
SCHEMBL49952 0.83 ALDH1A1 (0.70) MAPTPBRM1ALDH1A1MEN1KMT2A
SCHEMBL1009236 0.83 MAPT (1.00) MAPTAPPALDH1A1MEN1KMT2A
SCHEMBL5072017 0.82 LMNA (0.62) MAPTAPPALDH1A1MEN1KMT2A
SCHEMBL254959 0.82 APP (0.61) MAPTAPPALDH1A1SRD5A2
Ammonia Solution, Strong SCHEMBL28612928 0.81 ALDH1A1 (0.67) MAPTPBRM1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL8746067 0.81 ALDH1A1 (0.67) MAPTPBRM1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808804-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2014-08-19 — — US disclosed
US-8808804-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2014-08-19 — — US disclosed
US-20130101742-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY (US) 2013-04-25 — — US disclosed
US-20130101742-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY (US) 2013-04-25 — — US disclosed
US-8309663-B2 Water-entrained-polyimide chemical compositions for use in high-performance composite fabrication THE BOEING COMPANY (US) 2012-11-13 — — US disclosed
US-8106142-B2 Polyacetylinic oligomers THE BOEING COMPANY (US) 2012-01-31 — — US disclosed
US-20100204485-A1 POLYACETYLINIC OLIGOMERS THE BOEING COMPANY 2010-08-12 — — US disclosed
US-20080300360-A1 WATER-ENTRAINED-POLYIMIDE CHEMICAL COMPOSITIONS FOR USE IN HIGH-PERFORMANCE COMPOSITE FABRICATION THE BOEING COMPANY 2008-12-04 — — US disclosed
EP-1189973-B1 COMPOSITION OF AND METHOD FOR MAKING HIGH PERFORMANCE RESINS FOR INFUSION AND TRANSFER MOLDING PROCESSES NASA (US) 2006-09-20 — — EP disclosed
EP-1189973-A1 COMPOSITION OF AND METHOD FOR MAKING HIGH PERFORMANCE RESINS FOR INFUSION AND TRANSFER MOLDING PROCESSES The Government of the United States as represented by the Administrator of the National Aeronautics and Space Administration (US) 2002-03-27 — — EP disclosed
US-6359107-B1 FOR FABRICATION OF COMPOSITE PARTS, SUCH AS FOR AEROSPACE APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR, NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2002-03-19 — — US disclosed
WO-2000069948-A1 COMPOSITION OF AND METHOD FOR MAKING HIGH PERFORMANCE RESINS FOR INFUSION AND TRANSFER MOLDING PROCESSES THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2000-11-23 — — WO disclosed
US-5599993-A USED FOR ENDCAPPING POLYIMIDES WITH EXCELLENT SOLVENT AND CHEMICAL RESISTANCE, HIGH STRENGTH AND MODULUS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1997-02-04 — — US disclosed
US-5412066-A Adhesives THER UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1995-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204485-A1 POLYACETYLINIC OLIGOMERS AADAC, ACMSD, ECPAS MAPT 1019/4885APP 3468/4885PBRM1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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