Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812178 | 0.91 | CHEK1 (0.37) | ALKAR | |
| SCHEMBL16301320 | 0.88 | SLK (0.38) | ALK | |
| SCHEMBL3151398 | 0.86 | ALK (0.43) | ALK | |
| SCHEMBL1011211 | 0.86 | EGFR (0.39) | ALK | |
| SCHEMBL3137319 | 0.82 | PDK2 (0.41) | ALKAR | |
| SCHEMBL25836787 | 0.82 | ALK (0.34) | ALKAR | |
| SCHEMBL163723 | 0.81 | GSK3B (0.35) | ALK | |
| SCHEMBL6818231 | 0.80 | PARP1 (0.37) | — | |
| SCHEMBL25875884 | 0.80 | ALK (0.35) | ALKAR | |
| SCHEMBL165110 | 0.79 | PDK2 (0.40) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071401-B9 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL INC (US) | 2018-03-14 | — | — | EP | disclosed |
| EP-3071401-B1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20160279886-A1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL, INC. | 2016-09-29 | — | — | US | disclosed |
| EP-3071401-A1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | Transitions Optical, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2494408-B9 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2494408-B1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2015-04-15 | — | — | EP | disclosed |
| US-8647538-B2 | Photochromic compounds having at least two photochromic moieties | TRANSITIONS OPTICAL, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-8518305-B2 | Photochromic materials | TRANSITIONS OPTICAL, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2494408-A1 | PHOTOCHROMIC MATERIALS | Transitions Optical, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120136148-A1 | Photochromic Compounds Having At Least Two Photochromic Moieties | TRANSITIONS OPTICAL, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| EP-1872173-B9 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1872173-B1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090072206-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | JOHNSON & JOHNSON VISION CARE, INC. | 2009-03-19 | — | — | US | disclosed |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| EP-1872173-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1869140-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | Johnson and Johnson Vision Care, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110513-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-2006110221-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060226402-A1 | Ophthalmic devices comprising photochromic materials having extended PI-conjugated systems | KIM BEON-KYU | 2006-10-12 | — | — | US | disclosed |
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | TRANSITIONS OPTICAL, INC. | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228557-A1 | Photochromic materials having extended pi-conjugated systems and compositions and articles including the same | INCENP, PCNA, INTS6 | ALK 2838/4885AR 3809/4885 |
| US-20090032782-A1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | INTS6, INCENP, PCNA | ALK 2537/4885AR 3514/4885 |
| US-20120136148-A1 | Photochromic Compounds Having At Least Two Photochromic Moieties | CRY2, PCNA, MTCL3 | ALK 3290/4885AR 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.