Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 8/20 | 0.32 |
| ▸ | GAA | P10253 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108118 | 0.81 | CYP1A1 (0.50) | TDP1TSHRCYP1A1CYP1B1NOX1 | |
| Benzene SCHEMBL11416188 | 0.72 | MAOA (0.32) | — | |
| SCHEMBL9349266 | 0.68 | MAPT (0.39) | MAPTALDH1A1TAAR1L3MBTL1 | |
| SCHEMBL5560073 | 0.68 | ADRA2A (0.50) | TDP1TSHRCYP1A1CYP1B1NOX1 | |
| SCHEMBL3064895 | 0.68 | ALDH1A1 (0.50) | TDP1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL2554754 | 0.68 | ALDH1A1 (0.50) | TDP1TSHRMAPTGAAALDH1A1 | |
| Azobenzene SCHEMBL11590710 | 0.68 | ALDH1A1 (0.50) | TDP1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL1569120 | 0.68 | — | — | |
| SCHEMBL5754707 | 0.67 | MAPT (0.48) | TDP1MAPTGAAALDH1A1MEN1 | |
| SCHEMBL5751505 | 0.67 | MAPT (0.48) | TDP1MAPTGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824489-B1 | STEREOISOMERICALLY ENRICHED 3-AMINOCARBONYL BICYCLOHEPTENE PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS INC (US) | 2011-01-05 | — | — | EP | disclosed |