Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL10803509 | 0.72 | MAOA (0.82) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL9736077 | 0.71 | TDP1 (0.34) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7863864 | 0.70 | GAA (0.52) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL11335174 | 0.70 | GAA (0.52) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL275526 | 0.69 | MAOA (0.77) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL2470956 | 0.69 | MAOA (0.77) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL29785641 | 0.69 | MAOA (0.77) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL718626 | 0.69 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL10499209 | 0.68 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CPLAUKMT2A | |
| SCHEMBL10499203 | 0.68 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CPLAUKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253166-B2 | 6-phenyl-7H-pyrrolo[2,3-d]pyrimidine compounds that induce neuronal differentiation in embryonic stem cells | IRM LLC (BM) | 2007-08-07 | — | — | US | claimed |
| EP-0255704-A2 | Pyridazinone derivatives, process for their preparation and their use as medicines | Roche Diagnostics GmbH (DE) | 1988-02-10 | — | — | EP | disclosed |