Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787742 | 0.84 | CA2 (0.36) | TSHRALDH1A1 | |
| SCHEMBL3036592 | 0.77 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL2413342 | 0.77 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL12709934 | 0.74 | — | — | |
| SCHEMBL10098995 | 0.72 | FAAH (0.33) | TSHR | |
| SCHEMBL7819862 | 0.64 | — | — | |
| SCHEMBL22492555 | 0.63 | — | — | |
| SCHEMBL1607801 | 0.63 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL1118529 | 0.63 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL14351742 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094897-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-20110082182-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094897-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, HDGF | TSHR 4726/4885ALDH1A1 1469/4885 |
| US-20110082182-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | SARS1, VIP, MAVS | TSHR 4339/4885ALDH1A1 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.