Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 15/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099588 | 0.89 | MAPT (0.59) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL6296181 | 0.85 | HDAC4 (0.75) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL517309 | 0.85 | HDAC4 (0.81) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL12703834 | 0.84 | HDAC4 (0.69) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL6669511 | 0.83 | HDAC4 (0.85) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL6665592 | 0.83 | HDAC4 (0.85) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL1065393 | 0.83 | HDAC4 (0.85) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL137348 | 0.83 | HDAC4 (0.85) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL322121 | 0.82 | HDAC4 (0.67) | LTA4HHDAC1HDAC4HDAC7HDAC11 | |
| SCHEMBL7864815 | 0.82 | HDAC1 (0.77) | LTA4HHDAC1HDAC4HDAC7HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220151962-A1 | NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2022-05-19 | — | — | US | disclosed |
| US-8093227-B2 | Monosaccharide compounds and methods therefor | ALCHEMIA PTY LTD (AU) | 2012-01-10 | — | — | US | disclosed |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | ALCHEMIA PTY LTD. (AU) | 2010-07-22 | — | — | US | disclosed |
| US-7417129-B2 | Combinatorial libraries of monosaccharides | ALCHEMIA PTY LTD (AU) | 2008-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220151962-A1 | NOVEL INHIBITORS OF HISTONE DEACETYLASE 10 | HDAC10, HDAC1, HDAC11 | LTA4H 2212/4885HDAC1 2/4885HDAC4 9/4885 |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | SLC5A1, UGGT1, MRPL21 | LTA4H 1970/4885HDAC1 622/4885HDAC4 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.