Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099593 | 0.89 | LTA4H (0.68) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL3342586 | 0.83 | L3MBTL1 (0.80) | MAPTL3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL9222067 | 0.81 | SMN1; SMN2 (0.59) | MAPTL3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL21322008 | 0.80 | HDAC3 (0.64) | MAPTHPGDSMN1; SMN2HDAC4HDAC1 | |
| SCHEMBL12210902 | 0.80 | MAPT (0.66) | MAPTHTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10099561 | 0.80 | HDAC4 (0.56) | MAPTL3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL9888 | 0.80 | ALDH1A1 (0.86) | MAPTL3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL5969586 | 0.80 | CA1 (0.59) | MAPTL3MBTL1HTTALDH1A1HPGD | |
| SCHEMBL517309 | 0.79 | HDAC4 (0.81) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL6296181 | 0.79 | HDAC4 (0.75) | MAPTL3MBTL1HTTHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247496-A1 | 2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| US-8093227-B2 | Monosaccharide compounds and methods therefor | ALCHEMIA PTY LTD (AU) | 2012-01-10 | — | — | US | disclosed |
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | ALCHEMIA PTY LTD. (AU) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184607-A1 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR | SLC5A1, UGGT1, MRPL21 | MAPT 4099/4885L3MBTL1 2971/4885HTT 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.