Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | ICMT | O60725 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457436 | 0.92 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL2069635 | 0.90 | TP53 (0.59) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6629576 | 0.90 | ALDH1A1 (0.52) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL8041935 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL27526983 | 0.88 | TP53 (0.53) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL8329334 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10460057 | 0.88 | ADRA2C (0.53) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL817611 | 0.86 | NPC1 (0.59) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL4153728 | 0.86 | ACHE (0.52) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL10398306 | 0.86 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8147735-B2 | Semipermeable polymers and method for producing same | ELTRON RESEARCH & DEVELOPMENT, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20100006495-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-01-14 | — | — | US | disclosed |