Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099720 | 0.90 | MEN1 (0.62) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL2069635 | 0.84 | TP53 (0.59) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL7505138 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL7791465 | 0.83 | HDAC3 (0.51) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL8041935 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL10460057 | 0.82 | ADRA2C (0.53) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL18457436 | 0.82 | MEN1 (0.55) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL29588899 | 0.82 | ESR1 (0.42) | ALDH1A1TSHRMEN1KMT2ACYP3A4 | |
| SCHEMBL8329334 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL27526983 | 0.82 | TP53 (0.53) | ALDH1A1TSHRGLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431389-B1 | Azo dyes and process for the manufacture of [5-amino-2-(2-hydroxyethylamino)phenyl](2-hydroxyethyl)sulfone | BAYER AG (DE) | 1993-12-29 | — | — | EP | claimed |
| US-5107025-A | For monoazo dye synthesis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | claimed |
| JP-3181454-A | — | — | None | — | — | JP | disclosed |
| JP-11349834-A | — | — | None | — | — | JP | disclosed |
| CN-109689621-B | Compound, core-shell dye, photosensitive resin composition containing the compound and color filter | 三星SDI株式会社 | 2022-04-05 | — | — | CN | disclosed |
| EP-1317459-B1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| US-20030232875-A1 | Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2003-12-18 | — | — | US | disclosed |
| EP-1317459-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | AstraZeneca AB (SE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020530-A1 | BICYCLIC PYRROLYL AMIDES AS GLUCOGEN PHOSPHORYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-03-14 | — | — | WO | disclosed |
| JP-H11349834-A | AZO DYE | BAYER AG | 1999-12-21 | — | — | JP | disclosed |
| US-5278291-A | Color materials | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5107025-A | For monoazo dye synthesis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| JP-H03181454-A | AZO DYE AND PROCESS FOR THE PREPARATION OF (5-AMINO-2-(2-HYDROXYETHYLAMINO)PHENYL)(2-HYDROXYETHYL) SULFONE | BAYER AG | 1991-08-07 | — | — | JP | disclosed |
| EP-0299328-B1 | REACTIVE DYES | BAYER AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| EP-0271656-B1 | REACTIVE AMINO ALKOXY-TRIPHENE DIOXAZINE DYES | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4874857-A | FIBER-REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0271656-A1 | Reactive amino alkoxy-triphene dioxazine dyes | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |
| EP-0177414-A1 | Jodized triaminobenzene compounds, process for their preparation and their use in contrast products | GUERBET S.A. (FR) | 1986-04-09 | — | — | EP | disclosed |
| US-4014892-A | ANTHELMINTICS | AMERICAN CYANAMID COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3989835-A | Method of using 6-substituted amino phenyl-2,3,5,6-tetra-hydro[2,1-b]thiazoles for controlling gastrointestinal nematodes | AMERICAN CYANAMID COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232875-A1 | Bicyclic pyrrolyl amides as glucogen phosphorylase inhibitors | GYS1, GYS2, PYGL | ALDH1A1 3884/4885TSHR 1190/4885GLA 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.