SCHEMBL10100811

SCHEMBL10100811

COc1cc(-n2c3ccccc3c3ccccc32)ccc1-c1ccc(-n2c3ccccc3c3ccccc32)cc1OC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ HPGD P15428 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ PRKCA P17252 1/20 0.39
▸ GSK3B P49841 1/20 0.39
▸ LMNA P02545 2/20 0.38
▸ ROCK2 O75116 2/20 0.37
▸ PARP1 P09874 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ RXFP1 Q9HBX9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16900164 0.89 SMN1; SMN2 (0.42) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL18209347 0.88 SMN1; SMN2 (0.50) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL16521616 0.83 IDO1 (0.47) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL28001656 0.83 SMN1; SMN2 (0.47) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL21666814 0.80 ACACA (0.52) KDM4EL3MBTL1SMN1; SMN2MAPK1KMT2A
SCHEMBL14039032 0.79 ENPP2 (0.49) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL21671601 0.79 KDM4E (0.38) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL14648914 0.79 SMN1; SMN2 (0.44) KDM4EL3MBTL1ATMSMN1; SMN2MAPK1
SCHEMBL13980942 0.78 POLB (0.44) SMN1; SMN2MAPT
SCHEMBL14996011 0.77 KDM4E (0.58) KDM4EL3MBTL1ATMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9082996-B2 Organic electroluminescent element, display device and lighting device Konica Minolta, Inc. (JP) 2015-07-14 — — US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 — — US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 — — US disclosed
US-8053765-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-08 — — US disclosed
US-8053765-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-08 — — US disclosed
US-20100295026-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-25 — — US disclosed
US-20100295026-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-25 — — US disclosed
US-20090091253-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-09 — — US disclosed
US-20090091253-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-09 — — US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 — — US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 — — US disclosed
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