Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10100811 | 0.88 | KDM4E (0.47) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL31495214 | 0.87 | TUBB4A (0.49) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL14648914 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL28001656 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL16521616 | 0.85 | IDO1 (0.47) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL14039032 | 0.83 | ENPP2 (0.49) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL14019103 | 0.81 | MAPT (0.56) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL13049622 | 0.79 | KDM4E (0.39) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL16900164 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM | |
| SCHEMBL18780394 | 0.78 | L3MBTL1 (0.38) | SMN1; SMN2MAPK1L3MBTL1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-17 | — | — | US | disclosed |
| EP-3288951-A1 | FOUR-COORDINATE BORON COMPOUNDS | Dow Global Technologies LLC (US) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016178827-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-11-10 | — | — | WO | disclosed |
| WO-2016178827-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | C5, RBBP5, C2CD5 | SMN1; SMN2 2038/4885MAPK1 1423/4885L3MBTL1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.